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Patients affected with isolated glucocorticoid deficiency, a hallmark of hypopituitarism, usually retain a normal volemic status, in contrast to patients with primary adrenal insufficiency.
One of the first lessons gleaned from these large-scale studies is that hESCs are commonly diploid soon after derivation and can retain a normal karyotype after many passages (for example, in the ISCI study 66% of lines remained normal).
In the mitochondrion of LD-CMS, there is only one copy of atp6 linked with orf79, which is different from BT-CMS and HL-CMS, the mitochondria of which retain a normal atp6 (N-atp6) in its origin position (Itabashi et al. [2009]).
As highlighted in the following sections, most of the issues derived from it can be solved at the patient's bedside, the great bulk of patients belong to the subgroup exhibiting hypotonic hyponatremia and those with ill-tolerated hyponatremia either retain a normal ECFV or display a diminished ECFV.
These T-cell derived iPSCs ("TiPS") retain a normal karyotype and genetic identity to the donor.
These bacteroids retain a normal DNA content and are largely viable after isolation from nodules [6].
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Even under the most stringent feeder-free conditions without conditioned medium, human ESC exhibited an undifferentiated morphology, expressed markers of undifferentiated cells, demonstrated high alkaline phosphatase activity and multilineage differentiation and retained a normal karyotype.
The hPSCs cultured on PMVE-alt-MA maintained their characteristic morphology, expressed high levels of markers of pluripotency, and retained a normal karyotype.
The other cell line, H9, retained a normal XX karyotype after 6 months of culture and has now been passaged continuously for more than 8 months (32 passages).
We wondered whether the 3MC-fibrosarcomas produced in wt mice retained a normal response to DNA damage.
Additionally, lines were karyotypically normal after multiple passages and have been propagated for over 30 passages in culture while retaining a normal karyotype (Figure S3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com