Exact(3)
The comparison between the 1-year results of ORIGIN and other RCTs with a median length of 24 weeks favors ORIGIN (88 vs. 41.4%).
These results are consistent with and complementary to the results of ORIGIN, the only randomized clinical trial with a large number of participants and follow-up extending more than a few years.
Both the results of ORIGIN and analyses of prior studies, such as described here, argue that starting basal insulin before A1C has reached high levels can routinely restore control to ≤7.0%.
Similar(57)
We report the effect size as a result of origin as δ = e β, where β is the parameter estimate of the origin term, noting the log link in the model.
With imprinting, on the other hand, the resulting parent-of-origin effect makes the two reciprocal heterozygotes different from each other.
Clinical evaluations of traditional treatments, however, have complex methodological and practical challenges, depending on the goals of the research and the audience for the results (country of origin; or new host countries and new patient populations).
Results of tumour origin of the paired tumours that scored using MS-HRM and aCGH were stated on the left side of the table.
Moreover, the results of the ORIGIN trial are not going to put a final word on the long-debated question about the best time to initiate insulin treatment and whether maintenance of good glycemic control may convey any CV advantage.
Genomic imprinting is the epigenetic marking of genes that results in parent-of-origin monoallelic expression.
Genomic imprinting is the epigenetic marking of a subset of genes that results in parent-of-origin monoallelic expression.
Imprinting is an epigenetic phenomenon that results in a parent-of-origin effect.
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