The physical origin of the repulsion is harder to pinpoint, but may result from induced membrane curvature as a result of insertion of the farnesyl-polybasic anchor of K-Ras or the farnesyl-palmitate anchor of H-Ras into the inner leaflet of the membrane [17].
The positions where PNGS are absent in sequences from infant but present in maternal sequence are summarized in Table 3. PNGS changes generally occurred in the V1, V2 or V4 region, as a result of insertion, deletion or mutations for most pairs (2669, 1449, 1984 and 1084).
PCR was used to confirm that 5-FOA resistant strains were the result of insertion of the mutated intron in place of URA3.
If, however, the remaining character data is largely a result of insertion events, the relationship is unlikely to hold, as seen in the left panels.
By comparison, VP6 of CTFV showed no similarity with this rabbit protein (8 ), which may be the result of insertion of a sequence encoding a lagomorph protein into segment 7 of EYAV.
Because of their high copy number, Alu repeats have been a significant source of new mutations as a result of insertion and post-integration recombination between elements [ 12, 13].
Whereas the multiple basic amino acids at the HA0 cleavage sites of HPAI viruses, either as a result of insertion or substitution (2 – 4 ), allows the HA0 precursor to be cleavable by ubiquitous host proteases (5 ).
Plant transposable elements have long been known to cause changes in gene expression as a result of insertion or deletion in coding regions and gene promoters and their effect on RNA processing [ 14].
PCR analysis was performed in order to determine whether the clinical isolates had a pathogenicity island that was uninterrupted or one that was divided in two regions as the result of insertion of a single-copy of IS 605 element, similar to genotypes 3 described previously [ 26].
The two modules are only distantly related to each other, an observation that suggests the possibility that Pol ε evolved as a result of insertion and subsequent inactivation of a distinct polymerase, possibly, of bacterial descent, upstream of the C-terminal Zn-fingers, rather than by tandem duplication.
