All patients had satisfactory results in terms of function and pain.
Fractures necessitate hospitalizations in many cases and result in loss of function and autonomy of elderly people.
Alanine replacements of residues comprising L164, MIV165 167, E168, or E169 resulted in loss of function and protein instability (D. Gross and D. Silver, unpublished observations).
Back and neck disability are frequent in older adults resulting in loss of function and independence.
Both processes contribute to symptoms and can result in loss of function and disability [ 1, 3].
Aging is defined as progressive deterioration of cellular components resulting in loss of function and cell death.
Many sporadic and germline mutations of HRPT2 that encodes parafibromin result in loss of function and tumor development.
Criteria: End stage failure of both kidneys, resulting in loss of function and the need for regular dialysis.
The outcome measures were trajectories of history of early wheezing, doctor-diagnosed asthma by age 7 years, and results of lung function and methacholine challenge tests at 8 years.
Misrouting may result in loss-of-function and, potentially, the accumulation of defective mutants in cellular compartments.
