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Functional annotation of genes carried out for other enriched around TSS composite elements (AuxRE+/AuxRE-like+, AuxRE+/ABRE-like) also showed significant results for developmental and regulatory processes (Additional file 11, Additional file 12).
We used previously utilized RNAi constructs so that we could directly compare our results for developmental phenotypes with those of others who previously utilized the same RNAi construct as a quality control measure.
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Paul Bradshaw, from Scotcen, said: "Whilst previous studies have relied on test results for individual developmental areas, this is a more holistic measure designed to tell whether or not Scotland is succeeding to be the best place in the world for a child to grow up".
Likewise, we also compared the results for various developmental stages and abiotic stress conditions in Arabidopsis reported by Czechowski et al. using the same microarray data sets.
Data were abstracted from the NNFU chart including demographics, reason for referral and results of developmental assessment.
The PSC-derived cells would form the missing organ as a result of developmental compensation for the defect.
The skeletal muscle samples investigated in the current study used highly differentiated foetal and lamb muscle cells, and hence, it is unlikely that poised modification is a dominant feature of the H3K27me3 results for these late developmental stages.
Conclusions: These results have implications both for developmental screening policies and for early intervention programs.
The concentrations of CA-III in hemolysate samples from female WL-chickens (1-93 weeks old) and male WL-chickens (3-59 weeks old) were assayed using competitive ELISA, and the results (mean ± SD) for developmental changes are shown in Figure 8.
Mice nullizygous for E4B died in utero as a result of developmental defects in the heart, suggesting an additional role for E4B in developmental processes in this organ.
Some apparent abnormalities (for example minor ventricular septal defects) could therefore result from developmental heterochrony or indeed from developmental delay, resulting from the gene deletion itself.
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