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The consequences of such resulting misalignment are that there will be several base mismatches with the reference around the indel.
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In order to understand the dynamic characteristics of these machinery faults, a theoretical model of a complete motor-flexible coupling-rotor system capable of describing the mechanical vibration resulting from misalignment and unbalance was developed.
Results show that while managers feel competing pressure to resolve a profit gap using both tactics aligned with their strategy and tactics designed to cut costs, they are biased toward short-term cost cutting tactics in such situations – often resulting in misalignment with the firm's focal strategy.
Patient and respiratory movement, resulting in misalignment of the images and biases in CT-based attenuation correction, are important issues in combined PET/CT systems.
Particular care was taken to exclude any influence resulting from misalignment in the orientation of the load axis to the neutral fibre of the interface area by using a biaxial positioning device with an accuracy of 0.01 mm.
These could be distinguished from typical artefactual 'translocations' resulting from misalignment of reads to repeat sequences, because usually both 'breakpoints' of such events are joined to multiple partner breakpoints.
This exposure also leads to atrophy that is characterized by specific targeting of glutaminergic and GABAergic precursor cells of the cerebellum (especially granule cells) resulting in misalignment of Purkinje cells and ectopic and multinucleated granule cells.
5, 37 Age-related decreases in health-related fitness are important, since the resulting postural misalignment, balance deficits, and strength/power loss are associated with impaired functional mobility and an increased risk of falling.
In the NBP of wt RB69pol, the side chains of L561 and Y567 restrict the movement of the templating base; consequently, the same mismatch now requires that the incoming incorrect dNTP shift its position, resulting in misalignment of the 3′-hydroxyl group at the primer terminus, thus accounting for the observed low insertion efficiencies.
In the second and third row, a slightly different definition of the landmark location is used (especially the nose), resulting in misalignments for manual registration, where the two halves in the third column do not overlap in the nose and mouth regions because of scaling differences.
Different organs and sexes, and sequence variants in individuals are known to produce extensive alternatively spliced transcripts, resulting in misalignments and incorrect assembly between reads arising from the same genomic region [ 34].
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