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Exogenous fructose appeared to be catabolized through glycolysis, resulting in the accumulation of acetyl-CoA and the subsequent elevation of unsaturated fatty acids.
The conductivity of holey and/or continuous amorphous carbon support films commonly used in cryoET is decreased at cryogenic temperatures, resulting in the accumulation of charge during imaging.
Nipponbare resulted in the suppression of AMADH expression, resulting in the accumulation of 2AP at the level of KDML105 under the same growing condition (Vanavichit et al. 2005).
However, an extracellular glucose oxidative pathway in E. aerogenes was activated under the aerobic conditions, resulting in the accumulation of 2-ketogluconate.
The electrical conduction of their heart can even be altered, resulting in the accumulation of fluid in the lungs and difficulty breathing.
ROS have been shown to disrupt ER homeostasis resulting in the accumulation of misfolded proteins and induction of ER stress [35] [37], [42].
In the absence of the viral transactivator Tat, NELF and DSIF cooperatively promote the arrest of RNAPII on the HIVLTR, resulting in the accumulation of short transcripts [41].
Finally, we also applied deoxymannojirimycin (DMM), a reagent that inhibits the ER mannosidases and Golgi mannosidase I, resulting in the accumulation of high-mannose oligosaccharide structures (Figure S2E).
This was evident from the fact that the decrease in Tor activity increased the STRE activity controlled by Msn2/4 resulting in the accumulation of trehalose.
Ligand bound VEGFR-2 activates PI3K that phosphorylates the phospholipid PIP2 resulting in the accumulation of PIP3 that in turn activates AKT [26].
This perturbation of lysosomal function blocks autophagosomal trafficking, resulting in the accumulation of autophagosomes.
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