The evolutionary trajectory of a protein is guided by structural and functional requirements, resulting in constraints to its amino acid composition and sequence.
When multiple traits share an underlying genetic basis, they may not evolve independently, resulting in constraints on adaptation or even maladaptation [ 1, 29- 31].
When overlapping sets of genes encode multiple traits, those traits may not be able to evolve independently, resulting in constraints on adaptation.
Indeed, it is highly possible that his calls for anti-press laws may be heeded and may result in constraint of journalistic license.
Israeli occupation resulted in constraints on West Bank industrial development; investment capital remained scarce both in the West Bank and Gaza, and only the transportation infrastructure saw much improvement after 1967.
But other officials warned that Vice President Dick Cheney and Defense Secretary Donald H. Rumsfeld were still likely to oppose giving the United Nations virtual supervisory control over the political future of Iraq, out of fear that such a step might result in constraints on American forces.
These limitations result in constraints on the location of the reserved VMs and restrictions to the data location and movements.
That is to say, they have made it very plausible that, in the billiard ball wormhole case, the time travel structure of such a wormhole space-time does not result in constraints on states on spacelike surfaces in the non-time travel region.
The need for arboviruses to replicate in disparate hosts is thought to result in constraints on both evolution and host-specific adaptation.
The need for arboviruses to replicate in disparate hosts is often thought to result in constraints on both evolution and host-specific adaptation.
This structural transition might impose a high degree of local structural constraints, which results in constraints on the protein sequence alongside requirements to be flexible.
