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Slippage occurs when a junction becomes unbalanced due to transition of a chain linked by this junction from its active state into the dangling state.
Although the exact mechanism is not yet determined, one possibility is related to the fact that the MTRR c.66A>G (rs1801394) polymorphism can lead to a decrease in the MTRR enzyme activity [ 14] and, since the MTRR enzyme converts the MTR enzyme from its inactive form to its active state [ 10, 13, 14], such a decrease may result in plasma Hcy elevation and DNA hypomethylation.
It is likely that p63RhoGEF retains Gq in its active state by shielding it from the GAP PLCβ, thereby accumulating Gαq-GTP.
In our model, we establish that TCR engagement activates Boost from its inactive state (Boosti) to its active state (Boosta).
Inhibiting PDK results in reduced lactate levels by maintaining PDH in its active state (Stacpoole et al., 1997).
What is the status of GPCR protonation in its inactive (ground) state and in its active state?
Notably, this resistance was based on the inability to convert BAX to its active state.
In the absence of ethylene, the dimeric unit is in its active state.
5-Methyltetrahydrofolate-homocysteine methyltransferase reductase (MTRR; GenBank accession no. AF025794) maintains MTR in its active state.
Economic legislation is generally upheld if the state can point to any conceivable public benefit resulting from its enactment.
"Injury has resulted from its intended suppression," Judge McWeeny stated in his ruling.
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