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Intestinal organoids demonstrate luminal expansion in response to CFTR-activating agents Fsk and IBMX resulting from augmented fluid secretion, and the expansion is inhibited in the presence of a CFTR-specific inhibitor (CFTRinh172) (Supporting Information Figure S5).
About 76 % of the cost increase resulted from augmented hospital (inpatient) resource use [19].
The increase did not result from augmented transcription.
Increased vessel opacity did not result from augmented atherosclerosis, since atherosclerosis was not uniformly distributed throughout the ascending aorta.
Reduced NE-induced constriction in BHR may result from augmented sensitivity and number of β-2 adrenergic receptors due to elevated corticosterone [ 59] which may blunt α-1 adrenergic receptor-mediated constriction.
We hypothesized that if communication exists between tumor and immune cells, coculturing would result in augmented expression of genes associated with tumor malignancy.
We hypothesized that if communication exists between tumor cells and promonocytes, their interactions would result in augmented expression of genes associated with tumor malignancy.
This reduction in the expression of RCAN1-4 resulted in an augmented expression of PROK1-induced expression of IL-8.
In the present study, we demonstrate that the activation of the ATM-NF-kappaB pathway, resulting from increased IL-6 expression, plays a central role in augmented chemoresistance in lung cancer cell lines.
In the current study, we demonstrate that deletion of A2AARs in mice, resulted in delayed but augmented expression of inflammatory cytokines, specifically IFNγ and TNFα during infection suggesting that initial inflammatory response is essential in controlling the disease.
Improvement of CNS perfusion was a result of an increase of MAP, which in turn resulted from an augmented compensatory tachycardia, due to further decrease in preload parameters.
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