This hypothesis (Fig. 1) is difficult to prove, given the diversity of L-MSC populations and the resulting complicated methods to label and track them [14].
For a more realistic case of a linear strip-shaped TCR pass region, we could not evaluate the resulting complicated integral to obtain an analytical expression for the TF transfer function.
Because the resulting complicated fin efficiency expression is not convenient for further optimization calculations, the data from the present solutions is correlated for a suitable range of problem parameters.
The light of stars was caught in the photographic emulsion on the plates, and the resulting complicated shapes of galaxies reminded me of insects preserved in amber.
Belgian Finance Minister Johan Van Overtveldt was somewhat softer in his approach, saying a "no" result "complicates matters," but that the door remained open to resume talks immediately.
In many life sciences, negative results, complicated results, or attempts to replicate previous studies never make it into the scientific record.
Although these assays have shown reliable and reproducible results, complicated sampling procedures were required, they frequently involved cell destruction, and the obtained data was acquired at a specific time point (end-points) [19, 20].
As a result, complicated metabolic systems can be visualized by 'birds-eye-view' technology with quantitative multivariate calculation, whereas previous "bottom-up" approaches employ a focused, microscopic view of specific reactions and molecules.
Finally, in both cases, the initially negative TST result complicated the diagnostic efforts.
Overall, the high degree of heterogeneity in quality, reporting, and study results complicated the tasks of abstracting and summarizing data.
Since the accuracy of the parameter estimation process is quite important in PBPK analyses, these characteristics make the interpretations or extrapolations of the obtained results complicated.
