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The regular exercise resulted in a heritability of 1.0 (a).
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0, resulting in a heritability of 0.17 or 0.07.
Fitting model 2 on the probit-link scale resulted in a heritability estimate of 0.33, which is consistent with the underlying liability scale heritability estimate of 0.37 (Table 1).
The additive genetic variance was 0.036, which resulted in a simulated heritability of 0.036 for the weekly data (0.039 if the herd variance of 0.072 is excluded from the phenotypic variance).
This resulted in a high heritability of 0.8.
Trait phenotypes were simulated by adding a random environmental effect drawn from a normal distribution with variance σ e 2, which was chosen to result in a heritability (h) of 0.3.
There was no significant additive component for systolic blood pressure (SBP), resulting in a narrow heritability of 0 and a broad heritability of.45.
The polygenic genetic variance was estimated at 0.156, which resulted in a polygenic heritability in the underlying scale of 0.14 (s.e. = 0.020).
Note however that the environmental variance of fitness related traits usually is large, and that this will result in a low heritability of such traits even if they have some additive genetic variance (e.g., Foerster et al. 2007).
On average, simulation in the epistatic scenario resulted in a broad-sense heritability of 0.84.
This resulted in a higher heritability estimate for QUICKI at higher BMI levels (Fig. 2b).
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