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Figure 5 shows the fluorescence images of the resultant drug carriers toward human breast cancer (MCF-7) cells compartment.
The resultant drug release profiles were fitted to the Korsmeyer-Peppas model [ 9] to establish the predominant drug release mechanisms.
The resultant drug exposure from the unstudied dose being within the empirically studied range for the compound would be easier to accept from a regulatory point of view, though the possibility of extrapolation was not principally excluded.
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15.4 mg of tetrandrine (the mass ratio of tetrandrine to PC was kept to be 1 : 13 in each ethosomal system) was immediately mixed with the resultant drug-free ethosomes suspension under stirring at 700 rpm in a closed container.
The resultant of drug carriers could disperse homogeneously in aqueous solution, showing a superparamagnetic characteristic and could inductive magnetic heating with external high-frequency magnetic field (HFMF).
The natural product rapamycin binds to an intracellular protein known as FK506-binding protein 12 (FKBP12) and the resultant protein-drug complex inhibits the kinase activity of mTOR.
A key goal in the development of the dynamic in vitro lipolysis model has been correlating the in vitro data of various drug-lipidic delivery system combinations to the resultant in vivo drug profile.
The docking has been performed for the resultant seventeen approved drugs and two known inhibitors.
(via) In China there are some people who think a good way to make some cash is to grind up dead babies and sell the resultant powder as drugs.
The addition of KET to the spinning solutions did not affect the morphology of resultant fibers, and no drug particles could be observed to separate from the polymer matrix.
A report using 3xTg-AD mice (∼3 months of age) and APPSw/Ind mice (16 17 months) indicated that blood flow insufficiency should be prolonged enough to accelerate AD pathology; here, the use of captopril (a commonly used anti-hypertensive drug) and resultant modest inhibition (∼30%) of brain angiotensin-converting enzyme (Aβ-degrading) activity for 28 days did not affect Aβ catabolism [37].
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