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The high-copy number in these strains could be the result of transposition of another IS 6110.
The formation of these heterogeneous clusters is thought to be the result of transposition, ectopic recombination, or chromosomal translocations [ 77].
None of the other IS407A elements within this region contain the 4-bp complementary direct repeat, further signifying that these insertions were not a result of transposition but instead due to intrachromosomal recombination mediated by IS407A.
It is hypothesized that AM or XM factors are the result of transposition of the Y-linked M (Hiroyoshi 1964), and several lines of evidence suggest that M "inserts" into a single location on each autosome or X (Inoue and Hiroyoshi 1986).
With the exception of a fully preserved IS10 element present in the genomic sequence of PGB04 (likely the result of transposition from the bacterial host E. coli genome), all repetitive sequences appear to have accumulated a large number of mutations, deletions and rearrangements suggesting that these elements are no longer functional.
The kanamycin resistant clones obtained were only the result of transposition of Tn 5 from λNK467 to the bacterial DNA since in these conditions, λNK467 became a suicide vector because it cannot induce neither lytic cycle (mutation in the replication genes Oam and Pam) nor lysogeny (thermosensitive mutation of the repressor CI).
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Reference List [1] McGowan AJ: The Results of Transposition of the Ulnar Nerve for Traumatic Ulnar Neuritis.
The short isoform is likely the result of a transposition fixed by inbreeding in the early 1900s.
Insertion 02A-0001 is the result of local transposition, and thus is linked to the original concatemer of transposons.
As a result of replicative transposition, new copies of the Mu DNA occur at many sites in the bacterial genome, frequently within several kilobase pairs of one another.
Such low diversity of cultivated flax might be a result of low transposition activity and/or creation of bottleneck effect during flax selection.
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