Following traumatic peripheral nerve injury, proliferation of scar tissue from the epineurium will result in impediment to the regenerating axons that need to traverse the injury site.
Here, we show that the EGFR inhibitor gefitinib and the mTOR inhibitor RAD001 when used in combination improve effectiveness of the treatment in HER2 overexpressing breast cancers that results in impediment of cancer growth.
County planners or decision-makers frequently discovered that the lack of comprehensive evaluation of cost structure of waste disposal facilities may result in unexpected impediments in decision-making when putting the regional solid waste management program into practice.
This results in significant impediments on the success of semantic-based GP in solving real world problems, due to the additional computational overheads incurred.
Of the more than 50 clinically detected point mutations in Bcr-Abl, the majority occur in the ATP-binding pocket and appear to result in a steric impediment to drug binding [11], [13] [15].
In addition, for such systems, the effect of crystal forces on conformational change upon crystallization is decreased which results in an impediment of crystal growth.
At the end of the conference, a joint communiqué was issued and included the statement, 'We the conferees deplore war and we are committed to end the instability and destruction to our resources resulting in unjustified impediment of development' (see Additional file 1).
The limitation of detection methods, to a great extent, has resulted in an impediment to the research on O-GlcNAc modification.
To facilitate meeting all these obligations, the preferable focus should be promotion of ethical research, rather than the prevention of unethical research, which inevitably results in the impediment of researchers from doing their work.
For families in regional or remote areas, the centralisation of PICU services can result in distance and time impediments to urgently needed health care.
