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Major concerns arose from a sub-study of SWEN in India which reported that 92% of babies infected despite NVP prophylaxis harboured viruses resistant to NVP, thus jeopardizing the use of any drug of this therapeutic class (NNRTI) for future treatment of these infants, which restricts considerably the number of ART drugs available in low-income countries.
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That these restrict considerably the investments auditors in big practices can make is fair enough.
The current, narrowness, curves, and presence of exposed rock sills on the Alto Paraná restrict considerably the size of vessels, and several rapids can be passed only with the use of winches to pull the vessels.
Currently, no easy-to-use and yet effective methods are available to guide process synthesis and design, restricting considerably the applications and therefore the impacts of reactive distillation columns to the chemical process industry.
We do not believe, though, the sample homogeneity and smallness restrict considerably the relevance of the presented findings.
Yet, my enthusiasm is tempered greatly by the fact two of the other people on that list - Ana Marie Cox and Alex Balk - have since had their political hilarity restricted considerably by the end of RADAR Magazine.
However, the clinical use of DOX is restricted considerably by an increased risk of cardiotoxicity associated with DOX-induced cardiomyocyte apoptosis [ 27- 29].
Here, we examine the relationship between FST and the frequency of the most frequent allele, demonstrating that the range of values that FST can take is restricted considerably by the allele-frequency distribution.
In contrast to saturated linkers, using unsaturated linkers with substantially less connectivity considerably restricts the search space.
This considerably restricts the practical use of PC at the industrial level.
Low chemosensitivity considerably restricts the therapeutic efficacy of gemcitabine (GEM) in pancreatic cancer treatment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com