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With a less restrictive threshold of raw p-value < 0.05, CA1 and VIP showed overlap in some of these categories, though to a much lower degree (Supplementary Fig 4a and b).
In order to avoid this problem, a less restrictive threshold, i.e., μglobal, is used instead.
If looking for possible gene targets of transcription factors, it is advisable to use less restrictive threshold, resulting in more false positives but fewer false negatives.
In the foregoing studies, liberal RBC transfusion thresholds were similar to our restrictive threshold.
Moreover, fitting no. 8 did not surpass the restrictive threshold of 20 cfu/mL at 37°C.
When clinicians with the most restrictive threshold (7 g/dL) were excluded, the proportion rose to 84%.
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In accordance with recent expert recommendations, most prophylactic platelet transfusions were given using restrictive thresholds of 10 20 × 109/L in critically ill cancer patients with hypoproliferative thrombocytopenia.
For the identification of overrepresented binding sites in large gene sets, it is advisable to use more restrictive thresholds (a smaller number of random matches).
Only 1 SNP (less than 1.5% of the variants detected in each individual, and around 6% of the variants shared by the same family) per family on average passed this filtering process, showing that, even after using restrictive thresholds, additional information has to be used to select the most probable variants (Table 5).
Only PAUDA mapped a smaller amount of reads because it internally uses restrictive thresholds.
The degree to which restrictive thresholds have been adopted in neurocritical care patients remains unknown.
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CEO of Professional Science Editing for Scientists @ prosciediting.com