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"The unnecessarily restrictive recommendations will leave thousands, possibly millions, of patients in the UK with no choice but to continue to source their effective cannabis medicine from the black market," says Jon Liebling, political director at the United Patients Alliance.
In view of the potential side effects, more restrictive recommendations for sport need to be developed.
Subsequent, more restrictive recommendations limit carnitine supplements to those children with overdoses above 400 mg/kg.
1 With the low-risk equation, only 13 of 162 men (8%) and 1 of 85 women (1%) with a first MI would have qualified for primary prevention with statins, leaving ESC alone with increasingly restrictive recommendations on primary prevention with statins.
Based on level 1 evidence, hypertension is a well-recognized high-risk condition in diabetic subjects and even more restrictive recommendations have been published for the optimal control of blood pressure values in diabetic patients (ADA 2007; Fuster et al. 2006).
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This more "watch and wait" practice was in line with the restrictive national recommendations issued for oseltamivir pediatric use during the 2009 pandemic wave, which suggested cautious prescription under one year of age, regarding the absence of safety data among infants [ 16].
Such a perception may aid GPs in following restrictive antibiotic prescription recommendations.
The IHR Review Committee was concerned by the restrictive measures and provided recommendations on how they can be more effectively addressed (15 ).
We designed a study to evaluate the efficiency and feasibility of two approaches to identify the need to update clinical guidelines recommendations: 1) restrictive search strategies using PubMed Clinical Queries search filters for MEDLINE and 2) the use of PLUS database.
Liberal use of episiotomy for women having a vaginal birth is not recommended but was often inappropriately practiced across the hospitals in all four countries, demonstrating lack of adoption of the evidence-based recommendation of restrictive episiotomy.
In spite of the recommendations to use restrictive transfusion strategies, it seems that many clinicians still use a more liberal transfusion strategy, often termed the "10/30 rule" (Hb of 10 g/dl, hematocrit of 30%%) [31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com