I've read the Jaron Lanier book that you mention, which I thought was fascinating – I think one of the bits that's stuck with me, and would also seem to be relevant to the way you work, is his concept of design "lock-in", where keeping up with new technology actually ends up shepherding the creation process along quite restrictive lines.
Competitive pressures continued to break down many of the traditional dividing lines that had grown out of older and more restrictive job definitions.
The FAIRE analysis pointed to a significant nucleosome density difference between permissive and restrictive cell lines.
To gain molecular insight to this restricted expression, we compared histone modifications and nucleosome occupancy in this intron between expression permissive and restrictive cell lines.
Enacting restrictive time lines and prohibiting amendments to push through changes of this importance to millions of Americans, especially senior Americans, ultimately disenfranchises the public and hurts the political process.
Thereafter procedures have evolved along three lines: restrictive that interfere with intake of calories, malabsorptive that interfere with their absorption, and a combination of these two approaches.
"New Jersey is way out of line and restrictive by comparison".
But that little line of restrictive fine print in a neighborhood restaurant is sobering.
But he said the company might have to consider filing for bankruptcy protection because its main bank has imposed restrictive measures on its line of credit and the Experts might have trouble meeting its payroll next week.
Accordingly, IRF-8 repression in a restrictive myeloid progenitor cell line was partially alleviated upon treatment with histone methyltransferase inhibitors.
