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But lawyers for the residents say their clients are being intimidated and forced to move to more restrictive group homes that serve lower-functioning patients.
The restrictive group received mainly colloids, whereas the liberal group was treated exclusively with crystalloids [79].
More episodes of hypoxia were detected in the restrictive group as expected.
Overall, there was a nonsignificant reduction in 30-day mortality for the restrictive group.
The restrictive group received 54% fewer units of blood and 33% received no blood transfusions in the ICU, whereas all of the liberal group received transfusions.
The restrictive group was transfused if Hb level fell below 80 g/L, the liberal group if below 100 g/L.
For patients aged <55 years, those in the restrictive group had a 5.7% mortality vs. 13% for those in the liberal group (95% confidence interval (CI) for the absolute difference 1.1 13.5%; P = 0.028) [14].
Patients with Hb ≥90 g/l were randomized to either the "liberal" group (transfusion trigger of <100 g/l) or the "restrictive" group (transfusion trigger of <70 g/l).
However, protocol violations were more frequent in the restrictive group than in the liberal one (5.9 vs. 2.2%, p = 0.004) because of ischemic events or acute bleeding most of the time.
The restrictive group received mainly colloids, whereas the liberal group was treated exclusively with crystalloids [ 79].
Eighty-eight patients were randomized, 43 to the conventional group and 45 to the restrictive group.
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