Sentence examples for restriction point from inspiring English sources

S100A4 binds to the p53 protein and restricts the function of the G-S restriction point in the cell cycle.

Cancer cells subvert controls at work at this restriction point and remain in cycle.

Intervention at the point of ras-raf interaction may be particularly important as a restriction point.

Mitogenic GFs override the G1 restriction point and promote hepatocytes to transit into S phase.

The restriction point (R-point) marks the critical event when a mammalian cell commits to proliferation and becomes independent of growth stimulation.

Analysis of intracellular levels of cell cycle regulatory proteins revealed an arrest at the G1/S restriction point of the naive but not memory subset.

Therefore the repression of Rb family proteins by ESCC miRNAs contributes to the lack of G1 restriction point in ESCs (Wang et al., 2013b).

The GC model was further proposed as an alternative explanation for the concept of the restriction point, which we recently demonstrated as being controlled by a bistable Rb-E2F switch.

Alternatively, the cells can become reversibly arrested at the G1/S boundary (restriction point) of the cell cycle.

Moreover, the IL-2 signal in priming stage facilitates the proliferation of CD8+ T cells by advancing the restriction point of the cell cycle.

Cell senescence is a biochemical process exhibited by metabolically active cells whose cell cycles are frozen beyond the restriction point in G1 phase.