Sentence examples for restriction elements from inspiring English sources
Since literature on this topic is sparse, a controlled bushing prototype which accommodates a combination of long and short flow passages and flow restriction elements is first designed, constructed and instrumented.
The CTL selection pressure exerted by HLA-B27 may not be greater than that exerted by other HLA restriction elements early in disease.
Many studies have tried to correlate the magnitude and/or breadth of the CTL response with control of viremia in humans and for the majority of HLA restriction elements no such simple relationship exists.
Because only a limited number of class II genotypes can function as restriction elements for the CS repeat epitope, it was not unexpected to find only 1 of 28 persons consistently respond to the HLA-restricted (T1B 4 antigen (Table 5).
When possible, optimal epitopes and/or HLA restriction elements were predicted for unmapped dominant responses (see Experimental Procedures).
Immunomonitoring platforms typically concentrate on restriction elements associated with European ancestry, and such tools are scarce for Asian HLA variants.
This approach allowed us to directly concentrate our efforts on naturally processed tumor antigen-specific epitopes presented by a given MHC class II restriction element.
This was an interesting finding, since DRAG mice do not express HLA class I molecules, the restriction element for thymic differentiation of human CD8 T cells.
Using a panel of B-EBV transformed cells, we found that these specific CTLs recognized the cA1 peptide by the A*0201 class I MHC molecule, the same restriction element as the CTLs derived from gp160IIIB immunized donor BI.
To evaluate the vaccine induction of CD8 T-cell responses, 50% of the enrolled subjects were HLA-B7+ which is known to be the restriction element for the V3 (RPNNNTRKSI) CTL epitope.
To identify the restriction element we first tested the recognition by CD4+ T cells of peptide loaded autologous APC in the absence or in the presence of anti-HLA-DR, anti-HLA-DP and anti-HLA-DQ mAbs.
