Sentence examples for restriction activities from inspiring English sources

TRIM5αhu did not show notable late restriction activities against these lentiviruses.

Intriguingly, the C-terminal regions of TRIM5αag and TRIM5αcy proteins negatively regulated the late restriction activities.

Our results therefore demonstrate the variable late restriction activities of TRIM5α orthologues and paralogues.

In this report, we examined the late restriction activities and VLP encapsidation efficiencies of simian TRIM5α orthologues and related human TRIM proteins, and their late restriction activities against a panel of lentiviruses.

Our results demonstrated the variations in the late restriction activities among closely related TRIM5α orthologues and a subset of human TRIM family proteins, providing further insights into the late restriction activities of TRIM proteins.

Unexpectedly, C-terminal TRIM5αhu sequences mildly strengthened the late restriction activities of TRIM5αag and TRIM5αcy; while impaired late restriction activities were observed when the N-terminal region of TRIM5αrh was fused with C-terminal TRIM5αag or TRIM5αcy sequences (Fig. 6C).

The preparation obtained thus exhibited high restriction activity on λ DNA and linearized the plasmids pBR322 and pUC19.

A series of chimeric TRIM5α constructs indicated that the N-terminal region of TRIM5αag and TRIM5αcy are essential for the late restriction activity, while the C-terminal region of TRIM5αcy negatively regulates the late restriction activity against HIV-1.

We show that XMRV as well as MoMLV virions package Apobec proteins independent of their specific restriction activity.

TRIM5αag and TRIM5αcy showed little late restriction activity on SIVMAC1A11, SIVAGMTan-1, SIVAGMSAB-1 and HIV-2 production.

TRIM5αag and TRIM5αcy showed intermediate restriction phenotypes against HIV-1 and HIV-2, but showed no restriction activity against SIV production.