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Whether this restricting mechanism exists in the rat preimplantation embryo and rat ES cells is unknown.
Elevated GLCE levels in BPH (49% of the patients) and prostate cancer (21% of the patients) could indicate a disruption of the restricting mechanism(s) and a specific type of GLCE expression disorganization in this pathology, while a decrease in GLCE expression may be associated with specific prostate cancer subtypes.
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Taken together, these data suggest that clonal activation of Yap in hepatocytes is not sufficient to overrule growth restricting mechanisms at steady state, but is sufficient to regulate transcription of a large number of genes related to extracellular environment.
However, the model does not prove that the restricted diffusion mechanism is correct, only that it is a plausible mechanism.
Our objective is to introduce a new DA model to investigate whether a generic restricted diffusion mechanism offers a plausible explanation for the lag, overshoot, and hang-up features of evoked DA responses.
Secondly, the requirement for a sizable number of CENP-A nucleosomes to perpetuate an active centromere reduces the likelihood for inadvertent detrimental neocentromere seeding without the need for a tightly restricted assembly mechanism.
Abrasive loading superposed with impact due to abrasive particles are a dominating wear mechanism restricting lifetime in many different industries, for example mining and farming.
One of these undergoes spontaneous apoptosis as part of the homeostatic mechanism restricting the number of stem cells present at any one time [ 16].
Although the terminally winged seeds of T. speciosissima are not easily dispersed and tend to germinate in proximity to the maternal plant [ 16], it is unlikely that limited dispersal is the only mechanism restricting gene flow.
PDAC-associated S100A8 degradation may be governed by a regulatory mechanism restricting its function, but the release of peptides with their own biological activity might circumvent this phenomenon and modify tumor biology.
The iPhone and iPod Touch are perfect multi-media learning platforms (with restricted input mechanisms) for all ages and across all markets – who is going to innovate and disrupt with these?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com