Sentence examples for restricting iron from inspiring English sources

The most common is iron deficiency anemia from chronic blood loss, reduced dietary intake, and persistent inflammation leading to increased hepcidin levels, restricting iron absorption in the duodenum.

In turn, we hypothesized that hepcidin may mediate the risk of malaria and other infections by restricting iron availability (Ganz, 2009, Drakesmith and Prentice, 2012).

This process, highly conserved in evolution, is mainly aimed at restricting iron access to invading pathogens, while preserving iron availability to the benefit of the host defense (16).

Hepcidin controls the absorption and distribution of iron (Ganz, 2013) and is thought to play a role in the innate immune response by restricting iron availability for pathogen growth (Ganz, 2009, Drakesmith and Prentice, 2012).

The low levels of Fe incorporation despite high serum iron and the lower levels of sTfR that were also apparent despite high EPO together suggest that poor Fe incorporation in these children may at least in part be due to dyserythropoiesis as well as the effect of high hepcidin restricting iron availability.

Hepcidin restricts iron availability in the blood, and PRS-080 was developed to mobilize irons trapped in iron storage cells in certain patients with anemia of chronic disease (ACD).

And an extensive evaluation of anaemia related genes responding to infection of C57BL/6 mice with T. brucei was interpreted as evidence for increased iron storage and reduced erythropoiesis as a consequence of restricted iron availability [16].

This indicates that restricted iron availability to microglia reduces the production of Sema4A.

Most micro-organisms require iron for their growth and proliferation, hence limiting the release of iron into the blood by increasing the levels of hepcidin would result in restricted iron availability to the infectious agent.

The reduction in iron availability, however, may be explained both by the infection-related iron sequestration and the probable restricted iron intake by diet, due to the anorexia and the impaired intestinal absorptive function shown by fish suffering enteromyxosis [ 6, 87].

Slow corrosion rate and poor bioactivity restrict iron-based implants in biomedical application.