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It also reduces long-term trends in other time varying confounders by restricting case to control period contrasts to the one month referent window [ 1, 7].
This tendency toward conservative estimates could be exacerbated by restricting case ascertainment to those consulting and diagnosed by a physician although we found very few persons in a calendar year who had only consulted a non-physician for their knee injury (data not shown).
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However restricting cases to those with clear cell type did not affect risk estimates by at least 10% (data not shown).
We also performed analyses restricting cases to glioblastoma multiforme.
Similar results were seen when restricting cases to acute lymphoblastic leukaemia (Table 4).
Restricting cases to those with laparoscopic confirmation may capture more "severe" cases only (Kennedy et al. 2005).
We also reanalysed the data after excluding the cases detected by the screening or restricting cases to those who had previously attended mammograhic screenings.
Similar results were found when evaluating ≥2 doses of pentavalent vaccine versus zero doses and when restricting cases to severe rotavirus AGE (Table 4).
To examine possible effects of exposure misclassification due to residential mobility, we ran sensitivity analyses restricting cases to those diagnosed at ages < 5 years.
To see whether the risk estimates differ by histological type, we also re-analyzed the data after restricting cases to those with diagnosis of squamous cell carcinoma.
However, restricting cases to only those with a recorded intervention (such as endoscopy) or outcome (such as death) did not substantially alter the association with socioeconomic status.
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CEO of Professional Science Editing for Scientists @ prosciediting.com