Any examination restricted to gene orthologs precludes the identification of genes not conforming to a 1-to-1 orthology.
The analyses stratified by smoking status were limited in that only one case of lung cancer was identified among never smokers and precluded an analysis restricted to never smokers.
This independence between SDs and signal intensities implies that the observed correlation between SDs is not restricted to any particular range of signals, precluding the possibility that the effect of noise on weaker signals was responsible for the observed correlation.
To date, exon capture has largely been restricted to species with fully sequenced genomes, which has precluded its application to lineages that lack high quality genomic resources.
If knowledge by acquaintance is restricted to belief in propositions where one's epistemic situation precludes the possibility of error, critics might well be right in suggesting that we have a tiny body of knowledge secured by direct acquaintance.
In contrast, previous work has largely been restricted to analyzing only one of these outcomes, 1 11 thereby precluding their comparison.
An additional limitation of our meta-cross was that engineered mutations were restricted to individual sub-populations and therefore did not segregate, precluding the inference of interactions between these mutations.
However, it is important to note that such a control task does not preclude the possibility of non-specific effects that are restricted to the regions that are engaged by the main task of interest.
Microarrays are also restricted to regions of the genome amenable to unique probe design, which precludes repeat-rich regions and novel insertions that are hotbeds of variation and mutation [ 19- 22].
Additionally, data describing changes in CCS by salt marshes were restricted to the continental USA because poor estimates of salt marsh abundance elsewhere precluded calculations of their global abundance.
The large size of this protein precludes its access to intracellular proteases and its activity is restricted to the outer cell surface and extracellular space.
