Thus medication did not change the observed pattern in motor functioning for patients with Parkinson's disease, but only restricted its manifestations.
Simultaneously the relevance of anti-dsDNA antibody presence needs to be restricted to clinical manifestations, thought to be caused by anti-dsDNA antibody and within an appropriate time frame.
Lupus erythematosus (LE) is a heterogeneous disease ranging from mainly skin-restricted manifestations (discoid LE [DLE] and subacute cutaneous LE) to a progressive multisystem disease (systemic LE [SLE]).
The proband's x-rays revealed epiphyseal changes characteristic of multiple epiphyseal dysplasia associated with a collagen IX defect, with manifestations primarily restricted to the knees.
As the descriptive analysis of the results of clinical and US examinations indicated very low prevalences of pathology in Bamako and Koulikoro, the fitting of multinomial models for the changes of pathological manifestations was restricted to the data of children from Ségou.
In two ambulant cases, there was evidence of structural brain involvement, whereas in seven, the clinical manifestation was restricted to a dystrophic skeletal muscle phenotype.
Although yaws, like syphilis, is a multi-stage disease, yaws is primarily restricted to skin and bone manifestations.
The severe clinical manifestations are mainly restricted to the first and second pregnancies [16], when the levels of specific antibodies against placental parasite antigens are not high enough to confer protection [17], [18].
More severe manifestations of DM skeletal muscle disease were observed in Mbnl1−/−; Mbnl2c/c; Myo-Cre+/− KO mice, with complete absence of Mbnl2 protein expression restricted to muscle fibres.
Most manifestations of FAP are restricted to the gastrointestinal tract and include duodenal and colonic cancer as well as fundic gland polyposis.
Like in India's Bollywood the emotional attachment of North Korean protagonists is obvious but physical manifestations of desire are severely restricted.
