Exact(1)
"People have been seriously misled by stories told by people who have looked at Finland through their own, restricted lens," he says.
Similar(7)
In the mouse lenses, Foxe3 expression is similar to that of Pax6, with early expression throughout the developing lens pit becoming restricted to lens epithelial cells only during development [ 37].
As a point of interest, although a digression from the focus of this review, gene sharing is not restricted to lens crystallins and occurs extensively throughout the animal kingdom (Piatigorsky 2007).
In wild-type mouse samples, this protein was observed in some cells throughout the lens vesicle at E12, but was restricted to the lens epithelium by E15, as described previously [ 18].
Furthermore, due to the size of the cameras, we were physically restricted to a lens-to-lens distance of 85 mm, but human interpupillary distance has an average of 63 mm (Dodgson, 2004).
In addition, these studies have shown that early in lens development, not all DNA synthesis is restricted to the lens epithelium, with some elongating fiber cells retaining the ability to undergo DNA synthesis.
The lens is also capable of direct ascorbic acid uptake; however this accumulation appears to be restricted to the lens epithelium [ 52, 53].
This is consistent with the observation that NHS transcript expression in the anterior lens vesicle and fibre cells becomes progressively restricted to the anterior lens epithelium during lens development (12) and supports a role for NHS early in cell differentiation as opposed to junctional maturation.
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