Engineering of such GTs is, however, restricted by lack of practical and broad-scope assays currently available.
The study of reaction-system topology (the set of all participating reactions) has long been restricted, by lack of data, to small subsystems.
Our mechanistic understanding of HR is restricted by lack of structural information about the regulatory proteins that control filament activity.
We are restricted by lack of information on the cause of mortality or the status of lost to follow-up patients.
Furthermore, the validity of the collected data may be restricted by lack of standardized instruments which jeopardizes the meaningful comparison of economic evaluations [ 7].
Performance on other tasks may be restricted by lack of availability or access to amenities such as transport, or adherence to traditional gender roles.
For example, ART with oocyte donation is authorized in the UK but access is somewhat restricted by lack of donors (Culley et al., 2011; Hudson and Culley, 2011).
This study found that loss of social networks, loss of esteem, restricted mobility, lack of access to food rations, and lack of access to basic supplies contributed to nutritional vulnerability [ 12].
However, a usual finding when studying vitamin D deficient subjects of the elderly Caucasian population is a positive relationship between s-25(OH D and 1,25(OH)2D, implying that when s-25(OH D is low, production of the active hormone may be restricted by lack of substrate [ 16].
However they felt restricted because of lack of time, lack of peer and manager support and limited knowledge and skills of the research process.
The Mets remain restricted by their lack of organizational depth, which eroded with their off-season trade for Johan Santana.
