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Among game theoretic approaches, the prisoner's dilemma framework22 has been subject to much investigation, and spatially restricted interactions have been shown to promote the resistance of cooperative dynamics against cheaters, due to formation of cooperator clusters32.
It is remarkable that while we see restricted interactions between kermit2 and α5β1, the dominant negative kermit2 construct is effective at abolishing cell migration.
Furthermore, several AtATM-mediated IR-upregulated genes encoded orthologues of human HR proteins that are localized together and/or have restricted interactions with ATM in DSBs flanking chromatin (BRCA1) or with ATR in ssDNA microcompartments of S/G2 chromatin (RAD51, BRCA1, RPA, RAD17, FANCD2, BRCA2), or with the MCM complex when replication follows HR [20], [39], [105], [106].
In summary, coordinated interactions and restricted interactions both exist in the world of small, noncoding RNA.
This indicates that restricted interactions may be a regulatory pattern in the miRNA world.
While the urban doctors spent time cultivating supportive ties with their patients, these were somewhat restricted interactions and they did not typify every appointment.
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Gunkel et al., 1998 and Rongo et al., 1995 found that localization dependent translation of osk occurred in a highly spatially restricted manner only at the posterior and required a locally restricted interaction between trans-acting factors and osk.
It would also require posterior localization of osk and as Gunkel et al., 1998, determined, a locally restricted interaction with a trans-acting factor would occur at the posterior of the oocyte to permit translation.
The Polynesians did indeed pass through as they moved into Remote Oceania, but they now appear to have had relatively restricted interaction with the other inhabitants of the islands.
Thus interaction was observed for the four constructs containing the third and fourth coiled-coil regions but restricted interaction with the construct containing only the first three coiled-coil regions and no interaction detected with the constructs containing only the first two coiled-coil regions.
The new initiative, called the Prescription Project, is an outgrowth of an article published in January 2006 in The Journal of the American Medical Association in which a coalition of scholars and doctors proposed that academic medical centers across the country take the lead in restricting interactions between doctors and the health care industry.
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