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Exact(13)
Researchers have been working for decades to elucidate the monophenolase/diphenolase specificity on a structural level and have introduced an early hypothesis that states that the reason for the lack of monophenolase activity in catechol oxidases may be its structurally restricted active site.
The small value of the day-side active areas indicates a Halley-type surface of only locally restricted active areas or zones, while most of the surface is passive but hot with maximum temperatures above 300 K.
Furthermore, the group of patients showing movement impairment (ie restricted active movements), as described by O'Sullivan [ 4], was also excluded.
Exclusions criteria were: neck surgery, known vertebrobasilar insufficiency, any recorded malignancy or restricted active movement of the cervical spine.
What is known is that subfamily 4A P450s have restricted active sites, which is somewhat intuitive as evidenced by their proclivity to oxidize terminal methyl groups, an energetically unfavorable reaction.
In order to obtain accurate energies of high lying excited states and reliable 2DES spectra, extravalence virtual orbitals have been included using the restricted active space technique.
Similar(46)
Both the solution and gas-phase results obtained for 3 by using B3LYP, B3P86 or M06 are very similar to those from restricted active-space SCF second-order perturbation theory (RASPT2) with a very large basis set and large active space.
However, the mechanisms which restrict active caspases from causing complete apoptosis are poorly understood.
The lateral location of Nt-RhoGAP1 to the apically located RAC/ROPs suggests a role in restricting active RAC/ROPs from spreading beyond the apical dome membrane (Klahre and Kost 2006), a model that is quite easy to conceptualize.
Since cells grown in 2i/LIF completely lack the low-expressing subpopulation, these data confirm that NuRD indeed functions to restrict active transcription of these pluripotency-associated genes in ESCs.
Secondly, given that these types of facilities vary considerably with regard to layout and structure, [ 58] it is not surprising that a lack of appropriate indoor play space may restrict active behaviors and thus support prolonged periods of sitting and screen-use [ 59].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com