Because our clone ordering allows us to restrict interactions between clones to close pairs, misassemblies within correct clone contigs generally did not bring together sequence that was separated by more than two clone lengths.
RNAup (Mückstein et al., 2006, 2008) and intaRNA (Busch et al., 2008) restrict interactions to a single interval that remains unpaired in the secondary structure for each partner.
As we concentrate on the dual feedback between organisms and their (local) environment, we restrict interactions between individuals to competition for reproduction via nutrients.
Additionally, these proteins have relatively large flat surfaces, thereby hindering the binding of small chemical inhibitors, or even if binding occurs it is difficult to restrict interactions or functionalities on the large complex as a whole.
In general, we observe two effects of our approach: (i) the meeting probabilities increase as compared to a model which restricts interaction to the edges of the interaction network, and (ii) the meeting probabilities are asymmetric.
Gunkel et al., 1998 and Rongo et al., 1995 found that localization dependent translation of osk occurred in a highly spatially restricted manner only at the posterior and required a locally restricted interaction between trans-acting factors and osk.
It would also require posterior localization of osk and as Gunkel et al., 1998, determined, a locally restricted interaction with a trans-acting factor would occur at the posterior of the oocyte to permit translation.
The magnitude of this coupling constant in Ser-OGlcNAc strongly suggests a conformationally restricting interaction that is present in both the α-helical and random coil states.
The Polynesians did indeed pass through as they moved into Remote Oceania, but they now appear to have had relatively restricted interaction with the other inhabitants of the islands.
