Sentence examples for restrict inflammatory responses from inspiring English sources

While the predominance of Th17 cells induces the secretion of a large number of proinflammatory cytokines, Treg cells restrict inflammatory responses and are associated with immune-tolerance [ 28].

Restricted inflammatory responses in SL damaged skin were in parallel with massive up-regulation of chaperones indicative of the induction of UPR.

Taken together, our findings indicate that at the late stage of LPS stimulation, the host cell can restrict the inflammatory response by inducing negative regulators such as iNOS and Trim30.

The role of specific immunity directed at CII might consist of restricting the inflammatory response to the specific location of the joints.

Among these are nonpathogenic Th17 cells with regulatory properties that restrict tissue destruction during inflammatory responses and promote tissue remodeling and repair.

These results suggest that Fas has the potential to reduce the extent of secondary damage by interacting with microglia and leukocytes in the following ways: (1) inhibiting microglia activation thereby reducing pro-inflammatory cytokine production resulting in restricted neutrophil infiltration and suppressed inflammatory responses.

This may be compared to naked DNA vaccines which typically express limited amounts of Ag largely restricted to inoculation sites, have restricted access to professional APCs, and poorly activate inflammatory responses, unless combined with additional genetic adjuvants [28].

Microinjection of aggregated A β42 into the brain elicited an inflammatory response restricted to the injection site of the wildtype mice, characterized by massive infiltration of microglia/macrophages.

This suggests that if a hyperinflammatory phenotype is a mechanistic intermediate linking accelerated periodontal destruction and diabetes, it is likely to be a localized inflammatory response restricted to the gingival tissues.

Although hyperoxia has been suggested to induce time-dependent inflammatory responses [10], studies in animals are usually restricted to periods of up to 6 h of mechanical ventilation, limiting its clinical applicability [16 19].

We investigated the effects of ARE on inflammatory responses to further clarify the molecular mechanisms whereby ARE restricts the development of atherosclerotic lesions.