Exact(1)
We also show that adding a P1 P3 macrocycle to ASV enhances the inhibitor's resistance barrier by restraining flexibility to poise the inhibitor for binding.
Similar(57)
That could restrain its flexibility in adjusting to the changing fashion tastes of those fickle youngsters.
The structural model includes transverse shear flexibility, restrained warping, and centrifugal and Coriolis effects.
Compared with existing models, the presented model accounts for the cyclic strain hardening behaviour of the BRB's steel core, the flexibility of the restraining system, the flow of frictional forces, the longitudinal variation of the core axial load and strain, and Poisson's effects on the core cross-section properties.
Therefore, we engineered a disulfide bond between W104C and A128C in the PhoQ PD that restrains conformational flexibility in α-helices 4 and 5. PhoQW104C-A128C is responsive to CAMP, but is inhibited for activation by acidic pH and divalent cation limitation.
They're more restraining.
I was restraining myself.
That ignorance is restraining".
Restraining orders had been required.
If anything, they needed restraining.
Male I'm restraining.
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