Simple head-to-tail in-frame fusions of two proteins often result in non-functional proteins due to either incorrect folding or restrained ability to interact with other protein subunits [ 16].
Rather than restraining developers' ability to make money, the OFT's principles have the potential to help build a bigger, responsible children's apps market – with Apple, Google, developers and industry bodies important participants.
Gold bugs want to see golden handcuffs restraining the ability of central banks to intervene and states to spend, they want to remove any vestige of political control of the monetary system and fix it an arbitrarily chosen shiny metal in order to let free market forces take over.
Although some Bayesian analyses have been more recently developed to do so [8, 9], many require complex and time-consuming computing of the likelihood functions, restraining the ability to explore more than often too simple evolutionary scenarios and molecular models [10].
Id1 is a member of a family of 4 proteins (Id1-4) known to inhibit the activity of basic helix loop helix transcription factors by restraining their ability to bind DNA [11], [12].
Here, the N.F.L. owners have agreed not to hire you, and their agreement, obviously, restrains your ability to trade your services for payment.
The federal government places a strict limit on the number of H1-B visas it issues, and corporations often complain the cap restrains their ability to transfer highly qualified workers from foreign countries.
However, the point of these measures is to restrain the ability of politicians to muck around with the money supply.Such "limits" are an advantage even in tough economic times because they are a credible signal of the commitment of a government to keep politics out of monetary policy.
Thus, PIN1 apparently restrains the ability of calpastatin to inhibit calpain, maintaining calpain activity in endothelial cells.
But people don't like it because it will restrain their ability to spend money and do things that they otherwise couldn't do.
Furthermore, "financial constraints restrain the ability of domestically owned firms to innovate and export and hence to catch up to the technological frontiers" (Gorodnichenko and Schnitzer 2010, p. iii).
