The discussion in which you have to ask your child to be restrained, to be careful when they talk about their faith and their beliefs in public because, unbeknown to them, there are people out there who see them as a threat; who fear Muslims and loathe Islam.
However, frequency grid points are restrained to be real, so regularization Δg Λ = (Δg Λ )* should be added to (12) in the case of harmonic retrieval.
The chance of repeated chemical motifs is much higher in large molecules, which means that rather than restraining a given distance to a specific value, sets of distances and angles can be restrained to be equivalent with a defined tolerance.
Thus, C70 is restrained to be similar to C370 etc. Hydrogen atoms cannot be refined freely in structures of large molecules due to their small X-ray scattering factors, relatively large atomic displacements (resulting from their terminal positions), and overall poor resolution data.
Also, in order to reduce costly conformational sampling and obtain a native-like peptide backbone conformation, the peptide backbone is restrained to be near the native conformation during the docking simulation.
Chemically equivalent bonds to the disordered magnesium atoms were restrained to be approximately equal.
