Exact(35)
The team also investigated the impact of restoring expression of microRNAs in cancer cells injected into mice.
Restoring expression levels of the EF-hand calcium (Ca2+) sensor protein S100A1 has emerged as a key factor in reconstituting normal Ca2+ handling in failing myocardium.
Inhibition of DNA methyltransferase 1 (DNMT1) can reverse the malignant behavior of cancer cells by restoring expression of aberrantly silenced genes that are required for differentiation, senescence, and apoptosis.
Polyuria caused by down-regulation of renal AQP 2 in the ischemia-reperfusion induced ARF rats was partially restored by administration of LSB (40 mg/kg, i.p ., restoring expression of AQP 2, in renal inner and outer medulla.
Polyuria caused by down-regulation of renal AQP 2 in the ischemia/reperfusion-induced ARF rats was markedly restored by administration of YJT (100 or 200 mg/kg, p.o). with restoring expression of AQP 2 in the kidney.
The phenotype could be rescued by restoring expression of Importin-α2 in neurons using the elav-GAL4 driver: 67% of these animals had no axon tract errors while 33% had one defect.
Similar(25)
To restore expression of LRRC25, we constructed the lentiviral vector pLenti6.3/V5-TOPO-LRRC25.
Choline alphoscerate but not galantamine decreased astrogliosis and restored expression of AQ-4.
Fasting decreased the expression of IGF-I mRNA in both tissues, while re-feeding restored expression to control values.
2i/LIF can abrogate persistent-NPC interactions, recover poorly reprogrammed interactions, reinstate CTCF occupancy, and restore expression levels.
Restored expression of Betaig-h3 gene, not DCC gene, by transfecting cDNA into tumor cells resulted in a significant reduction in tumor growth.
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