Sentence examples for restores activity from inspiring English sources

The dramatic stimulation of enzyme activity by azide and fluoride restores activity in otherwise marginally active D32A variants to near wild-type levels, suggesting that these anions functionally replace the Asp 32 carboxylate.

However, the addition of Mg2+ restores activity.

Correcting the misrouting of misfolded mutant proteins often restores activity and addresses the underlying disease.

These screens identified a glycine to serine mutation of L30e, which specifically restores activity to an RNA variant containing a U that replaces a helix-capping G. Similarly, an asparagine to alanine mutation was found to suppress a substitution at a position where the L30e RNA nucleotide extends out into the protein pocket.

Reduction of this disulfide bond by beta-mercaptoethanol restores activity, indicating that mobility of the head domain of ISP is functionally important in the cytochrome bc(1) complex.

Increasing the concentration of R102A P450cin 10-fold restores activity to only ∼18% of that of the wild type, with a kcat value of 154.4 ± 12.8 min–12.8

Back-mutation of these residues to the consensus found in an active PTP domain was sufficient to restore activity [ 14].

These mutants are predicted to restore activity in the H266 variant (Table 1, "restorative" mutants; Figure 2b).

The hybrids were however not as active as the parent GAEL 1 against MiaPaCa2 whereas 6 restored activity comparable to 1.

Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity.

Tryptophanamides with aliphatic side chains were inactive whereas basic residues restored activity.