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A return to sport is not based on time alone, but also on restored muscle function, which is reflected in strength and jumping ability [90].
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It is one thing for someone with a hormonal imbalance to take an anabolic steroid to restore muscle function; quite another for an athlete to secretly take a performance-enhancing drug.
In the presence of paraoxon, obidoxime was the most effective oxime and therapeutically used concentrations (10 20 μM) were able to restore muscle function even in the presence of 1 μM paraoxon.
And they still must find efficient ways to introduce cells with the edited DNA into patients so that those "corrected" cells can establish themselves and restore muscle function.
We are now close to producing cells that can restore muscle function to damaged hearts, neurons that can replace parts of the brain damage by stroke or age, and cells that allow the growth of new cells to repair injured eyes.
Importantly, these procedures are not intended to restore muscle function.
Conversely, the extranuclear expression of HMGB1 in stressed myocytes could represent a mechanism to restore muscle function.
Stratos et al. [ 85] investigated whether systemically applied vitamin D could restore muscle function and morphology after trauma.
Therefore, a better understanding of the components and processes leading to the development of fibrosis is important for our ability to improve muscle repair, treat DMD, and potentially restore muscle function.
In contrast to the Y750W mutant, which is still capable to bind myosin and restore muscle function, the N758Y and Δ602 630 mutants neither rescue the defect in sarcomere organization nor bind to UNC-54 in immunoprecipitation experiments.
Physiotherapist-supervised rehabilitation is advocated in the literature in order to restore muscle function and strength and improve joint range of motion, as well as facilitate a safe and graded return to sporting activity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com