Thus, BAT-specific β3-adrenergic transgenic re-expression into β3-adrenergic knockout mice failed to rescue CL316243-mediated effects on food intake and minimally restored effects on oxygen consumption, indicating that a full stimulation required the presence of β3-adrenergic receptors in white adipocytes (Grujic et al., 1997).
For the sake of clarity, it is important to point out that the neutralizing proposition, n, could itself have a genuine ground for doubt, d1, so that even if (n & d) did not reduce the warrant for x, [(n & d) & d1] could defeat the justification for x because d1 would defeat the restoring effect of n.
Similarly to these studies, we also confirmed the restoring effect of candesartan on increased oxidative stress induced by cisplatin in rat testes.
These data may indicate that membrane hyperpolarization may contribute to the restoring effect of insulin on the potentiation of BK-induced vasodilation by Ang-(1 7) on diabetic microvessels.
But because the only alternative to renewal is differentiation, reducing renewal will always initially lead to an increase in differentiated cell numbers, the opposite of a restoring effect.
Also, glitazones (insulin-sensitizing agents used to treat patients with type 2 diabetes) have been found to have a protective and restoring effect on endothelial function.
The major part of this energy is used to overcome the restoring effect of the interfacial tension and dissipation; the remainder is converted into kinetic energy.
Moreover, and in contrast with its restoring effect on LPS-induced IκBα and NF-κB p65 phosphorylation, TAK-242 had no effect on stearate-induced IκBα or NF-κB p65 phosphorylation.
The restoring effect of NFATc1 overexpression on the matairesinol-induced inhibition of osteoclast differentiation was also confirmed by counting the number of multinucleated osteoclasts and measuring the activity of TRAP.
The restoring effects of hf-rTMS deserve particular interest also under the respect of potential therapeutic applications.
