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If that were to happen, the authority would have to restore signals and other equipment that might have been damaged.
Those objections are threatening to derail plans to restore signals to the entire New York region, a prospect that so concerns television executives that the chairman of one media conglomerate brought the issue up in a recent lunch meeting with Vice President Dick Cheney.
Wang et al. also found a stimulatory effect of BAY K-8644 in diabetic preparations, as we did in the uterus, suggesting that the number of Ca2+ channels may be reduced, as it could improve Ca2+ signalling in diabetic myometrium but not restore signals to the level found in non-diabetic samples.
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More than 50 compounds were evaluated in their ability to restore signal transduction using a calcium imaging-based bioassay utilizing the CNGA3-mutant E228K [2].
Network Rail spokesman Nick King said: "We have engineers out working to clear snow drifts, working to restore signalling systems and working to bring that line back into full operation.
TCRζ overexpression does not restore signaling in TNF-α-treated T cells [ 63].
This provides additional negative feedback that would act homeorhetically to restore signaling to normal levels.
The challenge is to restore signal-sensitivity pharmacologically, using pulse-treatment with rapamycin as suggested previously (Rejuvenation Res. 2008;11:801-808).
Thus, these results suggest that lymphoma B cells have impaired BCR-induced signaling, but that inhibition of phosphatases can restore signaling in these cells.
This effect was completely blocked by SB-431542 treatment suggesting that expression of T βRII can restore signalling induced by endogenous TGF- β.
DOI: http://dx.doi.org/10.7554/eLife.09183.009 10.7554/eLiFigure83.010 Figure 4 figure supplement 3. Actin-remodeling agents do not restore signaling downstream of 3-IB-PP1 treatment.
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