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Therefore, if this "access, repair, restore" model of the chromatin dynamics is critical for the successful DNA repair and cell cycle control, then it is plausible that misregulation or interruption of the DNA damage-specific chromatin disassembly/reassembly pipeline could potentiate cellular senescence.
However, if a baseline age of 47 years and time horizon of 40 years were applied to our model, as in the Sharma et al 27 model, the RESTORE model would predict a 0.26 QALY gain and an ICER of £10 412 for ranibizumab monotherapy relative to laser therapy alone.
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This study aims to validate a cavity shape optimization approach for improving the debonding resistance of dental restorations by carrying out fracture tests on restored model teeth with standard and optimized cavity designs.
Why recreate the wheel when plenty of restored Model T's are in the collector-car market?
The entire job cost $10,000 -- about what it would cost to buy a restored Model A today.
He owns four restored Model T's, and he built the one I was about to try.
A touring exhibition of Ford vehicles, including a restored Model T, and vintage tractors and trucks, with an art contest for children.
In 1991, Mr. DeMott, who is in the construction business and has his own restored Model A, convinced Ms. Megaro that it was time to restore the dormant car.
With a restored engine and electrical system, a two-door (plus rear hatch) pre-1971 series 2a is likely to be $30,000, and a mint-condition restored model can be much more.
If curiosity moves them, they drift across the dining room to look at a lovingly restored model room that the Colonel installed to advertise the motor court next door.
Furthermore, checkpointing (i.e., saving and restoring model runs midstream) should be supported.
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