Sentence examples for restore activity from inspiring English sources

Back-mutation of these residues to the consensus found in an active PTP domain was sufficient to restore activity [ 14].

These mutants are predicted to restore activity in the H266 variant (Table 1, "restorative" mutants; Figure 2b).

Nevertheless, faculty groups were soon able to restore activity.

The most common mechanism to inactivate p53 function in human tumors is missense mutations; several compounds have been developed to restore activity of mutant p53.

Previously we reported that the neutral alcohol-based thyromimetic HY-1 can selectively restore activity to a functionally impaired form of TR associated with RTH without over-stimulating TRα, which has been associated with undesirable side effects.

Since the deficiency of the P-glycoprotein (P-gp) at the blood brain barrier (BBB) in AD may aggravate Aβ deposition and the P-gp reversal agents display lower selectivity of the action, to selectively restore activity of the efflux pump is eagerly required.

The hybrids were however not as active as the parent GAEL 1 against MiaPaCa2 whereas 6 restored activity comparable to 1.

Tryptophanamides with aliphatic side chains were inactive whereas basic residues restored activity.

Correcting the misrouting of misfolded mutant proteins often restores activity and addresses the underlying disease.

The first type is reversible coking of the zeolite; the coke is burned off during regeneration, restoring activity.

The relatively non-toxic PAAs ISA 1 and 4 (IC50>1.5 mg/ml) restored activity to the inherently inert toxins.