Unliganded TRs are expected to repress TH-response genes, increase tissue responsivity to TH, and regulate the timing of developmental events.
For example, the regulation of hippocampal GR expression (McGowan et al., 2009) may induce 'evolutionary appropriate' responses such as increased vigilance, alertness to danger, responsivity to novel stressors and a willingness to explore new environments (Glover, 2011).
We found higher expression of TH-response genes in the absence of TH, decreased responsivity to induction by TH, and precocious initiation of developmental progression in tadpoles with both TRα alleles disrupted.
Neuroimaging data showed that yohimbine increased amygdala activity in response to fearful faces in women, whereas it attenuated amygdala responsivity to fearful faces in men.
Indeed, differences in cortisol and ACTH responses were observed between groups, suggesting differences in the HPA axis responsivity to stressful situations.
Habituation represents a progressive loss of behavioral responsivity to a stimulus as its lack of adaptive significance is recognized.
Successful program strategies described included program culture, responsivity to needs, and the focus on strengths.
Neurophysiological studies have disclosed various abnormalities of spinal, brainstem and cortical responsivity to external innocuous or noxious stimuli in primary headaches.
Thus, participants may have experienced within task affect responsivity to consistent wins and unexpected losses, which stabilized prior to the visual analog assessment.
Mixed evidence exists regarding the role of cognitive reactivity (CR; cognitive responsivity to a negative mood) as a risk factor for recurrences of depression.
The BJT-based photodetectors show increased responsivity to green yellow light region (500 600 nm wavelength) compared to conventional N-well/P-substrate diode.
