Certainly, there are teachers that do not connect with their students any better than a machine but if the reward for students' responsiveness is ultimately a grade, it is not as powerful a tool as a genuine feeling of achievement of something that is beyond a grade: it's a connection to another human being who cares enough about his or her students to treat them as individuals.
Since changes in gene expression, either through mutation, epigenetic regulation, or differential splicing events, influence tumor development, progression, drug responsiveness and ultimately the survival of the patient, the identification of the tumor subtype and its genetic fingerprint is essential.
In this model, the authors had previously shown that iNOS-/ mice presented with improved microvascular catecholamine responsiveness and, ultimately, enhanced survival [ 2].
Increased responsiveness is ultimately expected to result in a stronger health, such as an increase in user satisfaction or service utilization, or a decrease in the prevalence of disease, in our case maternal mortality.
This combined clinical and genomics model approach can also be used to build predictors of therapy responsiveness, and could ultimately be applied to other tumor types.
The present identification of gene signatures of metronomic CPA responses and their upstream regulators will help elucidate underlying mechanisms and facilitate the development of clinically useful biomarkers of tumor responsiveness; such markers will ultimately be required for translation to the clinic to identify clinically effective metronomic regimens and responsive patients.
In this study, we sought to develop a transplantation vehicle to ultimately enhance the responsiveness of neural transplants to injury-induced SDF-1α.
The intraovarian actions of estradiol act to ultimately enhance follicular responsiveness to gonadotropins, and thereby result in increased aromatase activity and further estrogen synthesis [ 17, 18].
But, ultimately, Gary V is about responsiveness; on a recent flight to Australia, he replied to e-mails from October.
The main expected benefits of decentralisation were local participation in the planning of the services, increased responsiveness to locally-experienced problems, and ultimately increased efficiency and quality.
