To better understand the molecular basis of the interactions between ketamine and ORs, we used sequence comparison and molecular modeling to design mutations that (i) increased, reduced, or abolished ketamine responsiveness in responding receptors, and (ii) rendered nonresponding receptors responsive to ketamine.
Bees of the high-responsiveness group responded more to the CS+ than bees of the low-responsiveness group (Fisher exact test: p<0.005) while no differences were found for the CS− (NS).
We evaluated 96 colloid fluid loading events (200 to 600 mL given in three consecutive 30-minute intervals, guided by increases in filling pressures), divided into groups of responding events (fluid responsiveness) and non-responding events, in patients with low GEF (<20%) or near-normal GEF (≥20%).
The same result was conveyed by plotting the learning curves of bees with lower gustatory responsiveness (did not respond to sucrose at ≤0.1% in H2O, N = 63) toward those with higher gustatory responsiveness (did respond to sucrose at ≤0.1 in H2O, N = 327).
The last dimension is defined as an "outcome dimension", as it concerns the political system's capacity to respond (responsiveness) to citizens' questions (Morlino 2011).
With respect to norepinephrine responsiveness, WT mice responded to catecholamine application at 6 h after sepsis induction with increased CO, brought about by an increase in heart rate (Fig. 2e h).
In SHINE, FOI is operationalized to include the delivery process (how regularly and timely intervention commodities [latrine, soap, LNS] are delivered, and what VHWs do), the quality of delivery (how well they do it), and participant responsiveness (how households respond) [ 40].
Care and responsiveness refer to the fact that responsibility is always related to "responding to somebody", to "giving an answer".
Layers of bureaucracy and short-term political priorities create major inefficiencies, emasculate local management, thwart local responsiveness and encourage creative accounting in responding to Whitehall target-setting.
To determine responsiveness 30 patients were invited; 22 patients responded (response rate 73%) the first time, and 15 of them completed the FAOS twice (response rate 68%).
