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Lowering the thresholds for MYCN responsiveness leads to a larger group of overlapping genes.
This increase in responsiveness leads to pain hypersensitivity.
This physiological responsiveness leads to a series of changes at the protein level as an adaptive response to water stress.
Benes and colleagues' study is now the third study showing that targeting preload responsiveness leads to improved outcomes after major surgery [ 5, 6].
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3 It was previously thought that loss of androgen responsiveness led to mCRPC development.
Asthma is a chronic inflammatory disease, associated with airway hyper responsiveness that leads to recurrent episodes of wheezing, shortness of breath and chest tightness [ 1].
The idea of using heart lung interactions to challenge preload responsiveness has led to other novel tests, less studied than the ones detailed above.
Low output with evidence of normal biventricular systolic function should prompt investigation of volume status (Step 4): overt hypovolemia or presence of volume responsiveness will lead to fluid infusion.
The requirement for increased responsiveness has led to the development of new modular concepts which provide the bases for achieving higher system adaptability through increased component/module interchangeability and reusability.
The plethora of studies on sucrose responsiveness has led to the general idea that this unique behavioral trait can explain diverse behavioral responses [23] to stimuli as different from sugar as odors or light [24], [21].
Whether the presence of preload responsiveness should lead to the decision to infuse fluid, however, is still uncertain.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com