Exact(7)
Compared with the responsiveness induced by parenteral administration of BSA emulsified in Freund's complete adjuvant (FCA), oral immunization with the silica/BSA formulation produced a stimulated humoral and mucosal (sIgA) response.
The present study evaluated the SBA-15 capacity to modulate the immune responsiveness of High and Low responder mice immunized with BSA encapsulated/adsorbed in SBA-15 by the intramuscular or oral route and the adjuvant effect was compared with the responsiveness induced by BSA in aluminum hydroxide salts or emulsified in Incomplete Freund adjuvant.
In 1973, Tim Bliss and Terje Lømo described a phenomenon in the rabbit hippocampus that appeared to meet Hebb's specifications: a change in synaptic responsiveness induced by brief strong activation and lasting for hours or days or longer.
Specifically, in a rat pretreatment model simvastatin decreased NO overproduction and reverted the impaired vascular responsiveness induced by endotoxic shock [ 14].
While HDACi block restoration of alveolar macrophage GC responsiveness induced by theophylline or HDAC overexpression [ 62, 78], experiments directly examining the influence of HDACi on asthma and COPD alveolar macrophage activation have not been reported.
These specific effects are characterized by an aggravation of the reduced myocardial β-adrenergic responsiveness induced by diabetes and a particular redistribution of β-adrenoceptors, more specifically the appearance of a reduction in the β2-adrenoceptors expression and a normalization of β3-adrenoceptors expression.
Similar(53)
The passive leg-raising (PLR) maneuver provides a dynamic assessment of fluid responsiveness inducing a reversible increase in cardiac preload.
The ACIP guidelines ) has recently been changed for adults > 19 years old with immune-compromising conditions due to increasing evidence of immunological hypo-responsiveness induced by prior vaccination with PPV23 and reduced effectiveness of PPV23 [ 16, 17].
The "bimodal" and transient nature of IL2R expression would explain the many apparently conflicting observations in the literature for over three decades or more, where IL-2 appeared to stimulate either a predominantly effector or predominantly regulatory immune response, inducing either detectable responsiveness or tolerance.
In the two-injection protocol, changes in responsiveness are induced by the first psychostimulant administration and are revealed by the second one.
In keeping with this, CD3/CTLA-4 co-ligation prevented apoptosis under the same conditions where T-cell non-responsiveness was induced.
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