CKD patients are often treated with iv iron therapy in order to maintain iron stores and erythropoietin responsiveness, also in the case of not being iron depleted.
Although the literature contains varied definitions of responsiveness, in this case, it is used to indicate the ability of a measure to detect change [ 19].
The first cutoff allows the practitioner to exclude the diagnosis (fluid responsiveness in the present case) with near-certainty (that is, privilege sensitivity and negative predictive value), whereas the second cutoff is chosen to indicate the value above which the selected diagnosis can be included with near-certainty (that is, privilege specificity and positive predictive value) [ 101].
In fact, correlated responsiveness has been observed in the case of stimuli that are related to the appetitive search for food in which bees engage as foragers [21], [24], [23].
Critics argue that while consumers prefer the private sector due to perceived quality, easier access, and greater responsiveness, in many cases, the care provided in under-regulated developing country settings is of poor quality, with potential adverse implications for individual health outcomes as well as population disease control and drug resistance [2] [7].
This paper explores RRI's idea of mutual responsiveness in the light of recent RRI case studies on private sector research and development (R&D).
This aspect may become increasingly important if automated systems are established and caregivers play a supervising instead of an acting role with their knowledge and human responsiveness still being of importance, especially in the case of rapidly evolving clinical conditions and technical failures.
Therefore, after fluid loading and correction of left ventricular collapse the LV EF may not systematically increase even in the case of fluid responsiveness and increased inotropy.
By transferring a consistent amount of venous blood from the legs and the splanchnic compartment toward the intrathoracic compartment, it increases the mean systemic pressure [4], the cardiac preload and consequently cardiac output in the case of preload responsiveness of both ventricles [5].
In the case of fluid responsiveness, PLR increased venous return by increasing Psm to a larger extent than CVP.
